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  • SlowFoodFast sometimes addresses general public health topics related to nutrition, heart disease, blood pressure, and diabetes. Because this is a blog with a personal point of view, my health and food politics entries often include my opinions on the trends I see, and I try to be as blatant as possible about that. None of these articles should be construed as specific medical advice for an individual case. I do try to keep to findings from well-vetted research sources and large, well-controlled studies, and I try not to sensationalize the science (though if they actually come up with a real cure for Type I diabetes in the next couple of years, I'm gonna be dancing in the streets with a hat that would put Carmen Miranda to shame. Consider yourself warned).

Questionable sodium study, even more questionable comments

A new European study that purportedly shows low-sodium diets to be ineffective in preventing high blood pressure, and even more unlikely, that they increase the risk of death from heart attack or stroke, is being published in the May 4 issue of JAMA, and predictably it’s already excited a variety of comments in Gina Kolata’s current New York Times article from the CDC and from…Dr. Michael Alderman.

Predictably, because the CDC researchers think too few people were studied for too short a time with unreliable methods (24-hour urine collection to measure sodium intake indirectly, after the fact as it were.)

Alderman’s reaction was also predictable: he’s still insisting that only a nation-wide feeding study sort of clinical trial that follows its subjects until they die is sufficient to prove a true link between sodium intake and cardiovascular disease. Something so expensive and unwieldy it couldn’t be completed even if it were started, and we’d still be waiting around 30 years later wondering if salt had anything to do with heart attacks or strokes. Very convenient for the processed food industry, but pretty useless for public health. And also conveniently, Gina Kolata found more than one expert to say so.

What she didn’t find, but could have, is that a number of large-scale feeding studies have already been done and shown that eating a balanced lower-sodium diet helps reduce blood pressure and prevent blood pressure increases. DASH-Sodium is one of them. And no one had to wait until the study subjects died to figure it out.

Age, salt and the new USDA dietary guidelines

Last Monday the USDA released its latest version of the Dietary Guidelines for Americans (nominally dated “2010”). I was driving home and NPR carried USDA Secretary Tom Vilsack’s speech, in which he listed a few of the new highlights: eat less, eat less food with solid fats, eat less processed food, eat more vegetables and fruits, eat less sodium.

How much less sodium? About 2300 mg or 6 grams (1 teaspoon) of table salt per day, he said, is the recommended maximum for healthy adults, in line with the long-standing National High Blood Pressure Education Program’s guidelines, which are shared by the American Heart Association and many other professional medical groups.

There’s a second lower-sodium recommendation for anyone overweight, African-American, with heart or kidney disease or high blood pressure or diabetes, and anyone middle-aged or older. This year, as the more specifically heart-health-oriented professional organizations already recommend, the USDA guidelines set the lower maximum at 1500 mg per day, or about 3 grams of table salt.

And you’d think that was great, and I do, that the USDA guidelines have finally caught up with what the medical associations have been demanding based on the overwhelming weight of studies on dietary sodium intake as it affects blood pressure, cardiovascular disease including stroke, and kidney disease.

But there are two catches hidden in the midst of all this, and I’m not even sure Vilsack was aware of it. Smaller one first: Middle-aged? How old is middle-aged?

“Fifty-one and older,” Vilsack said. Whew, I thought. Four more years before I have to start thinking of myself as middle-aged. By the time I get there, I’m hoping the standard will have gotten fudged upward by at least another decade or so.

Because, you know, if you’re not 50 yet, 51 sounds reasonable–and comfortably remote for a lot of younger adults. Which I am, thank you very much. Don’t look at me like that.

So here’s Catch-51: When I was working at the National Heart, Lung and Blood Institute back in the mid-’90s, the general working recommendation for lowering sodium to 1500 mg/day was all the other high-risk groups Vilsack mentioned…and healthy adults 40 and up. Not 51 and up.

The choice of a cutpoint at age 40 for otherwise healthy people was based on the risk data from the first three National Health and Nutrition Education Surveys, which began collecting data across the nation starting in the 1970s. The latest version collected data around 2006 and its findings were just released last spring by the Centers for Disease Control. All the NHANES studies correlate  in-depth interviews about diet, exercise and lifestyle patterns, and cardiovascular history along with clinical health measurements (height and weight, blood pressure, cholesterol, urinary sodium excretion, blood iron, etc.) from thousands of ordinary Americans. Even early on, there appeared to be an independent higher risk and a greater need to lower sodium at 40 and older, all other health risk factors being equal.

But of course 40 seems too young to be middle-aged. And the USDA, which issues the Dietary Guidelines for Americans, tends to downplay certain elements of the risk statements so that no one, or at least not the agency’s chief constituents, gets upset. The no one in this case might easily be the Continue reading

FDA Regulation–Too Slow on Salt?

The Washington Post carried a story today that the FDA is finally getting a move on and planning how to regulate salt in processed foods–after numerous and repeated failures of laissez-faire voluntary self-regulation attempts. It’s been a long time coming; the FDA has been petitioned repeatedly by the American Heart Association, the Center for Science in the Public Interest, and many other organizations, both private and governmental, and has always maintained up to this administration that salt was a “generally recognized as safe” ingredient.

So I’m glad that the FDA is finally making some effort to regulate sodium in food and drop the “generally recognized as safe” status. I’m unfortunately not amazed at all that they’re trying to drag it out to a 10-year process. People’s taste for salt can be downshifted significantly in two or three weeks on average, so there’s really no excuse for such a gradual decrease except for the manufacturer’s cost of reformulation. They seem to be pacifying the processed food manufacturers–all the classic  prechewed food industry claims about reduced customer satisfaction appear to be overtaking discussion and usurping the issue of health risk.

But what really gets me is the last quote in the article:

“Historically, consumers have found low-sodium products haven’t been of the quality that’s expected,” said Todd Abraham, senior vice president of research and nutrition for Kraft Foods. “We’re all trying to maintain the delicious quality of the product but one that consumers recognize as healthier.”

Tell the truth: Those foods aren’t really all that delicious now. It’s like admitting that heavy salt is the predominant flavoring (the other being cardboard).

Salt reduction vs. hypertension meds–which would you choose?

One of the big complaints processed food companies, physicians in clinical practice, and the great gourmet media all have in common is that cutting back on salt would make food taste flat, and you as an individual wouldn’t necessarily get a big drop in your personal blood pressure from doing it. They argue that only “salt-sensitive” people have to worry about their intake, and anyway, a few points lower, they all say, isn’t really impressive enough to give up your 300-mg serving of sodium in a bowl of Kellogg’s raisin bran or 390 in a slice of La Brea sourdough. And don’t, for g-d’s sake, ask your favorite name brand celebrity chefs to stop salting early and often in each dish!

A big statistical modeling study in the New England Journal of Medicine this week knocks all this wishful thinking on the head, and does it very nicely. The study looked not at individual blood pressure drops but the health and cost benefit of dropping average salt intake by 3 grams a day over the entire U.S. population.

The researchers found that if everyone drops their salt intake back down, the benefits start to look like the ones from quitting smoking, cutting cholesterol and saturated fat, and losing weight to get to a normal BMI.

That’s because even when individual blood pressures drop by only a few points, they’re not going up (as they are today), and when a small average drop happens in a very large group, the big bell curve of disease shifts toward lower risk of consequences and later starts for developing heart disease and high blood pressure. After the first national cholesterol lowering guidelines were issued in the late 1960s, the nation’s heart disease and stroke risk dropped by about a third, and at least until obesity and blood pressure started to cause a back-reaction, the average age for a first heart attack went from 50 to 60 in men. That’s a huge kind of benefit.

The combined drop in heart disease and stroke deaths from cutting salt would be something like 200-400,000 people per year, a lot more than can be saved by simply putting everyone on blood pressure medications–the study made that comparison directly.

Altogether, a solid recommendation for dropping sodium levels in processed and restaurant foods, which make up about 80% of today’s sodium intake. And for not imitating processed food and chain restaurant thinking in your professional or home cooking, as Francis Lam seems to in his Salon.com commentary on the new NYC Department of Health initiative. And if there was any doubt that the Culinary Institute of America has been training Continue reading

Getting the Salt Out: NSRI and Voluntary Compliance, Again

In the wake of its city-wide diabetes reduction and restaurant nutrition labeling initiatives, the New York City Department of Health is leading yet another dietary health campaign, this time one that involves a national coalition of cities, states, and medical organizations. My hat’s off to them, even though I think the demands they intend to make of the food industry are much too light and much too toothless.

The National Salt Reduction Initiative, announced on Monday, will  encourage “voluntary compliance” from the processed food and restaurant industries to lower their sodium content by about 20% over the next 5 years. That’s pretty modest considering that both industries have doubled the standard sodium content of many common foods in the past 20-30 years, and that the national obesity epidemic seems to have coincided pretty nearly with that trend.

The UK’s national salt reduction campaign, which started in 2003 and serves as a model for NSRI, has government backing and its goal is 40% reduction of sodium in processed foods within 5 years, not 20%. They seem to be getting there, too.

NSRI’s coalition includes the Los Angeles Department of Health and a variety of medical organizations like the American Heart Association and the American College of Cardiology. What it doesn’t include this year, to my surprise–and, frankly, dismay–is involvement, funding or guidance from the National Heart, Lung and Blood Institute at NIH.

Ten years ago the NHLBI would have participated one way or another in encouraging this sort of initiative, but that was before the Bush years. NHLBI has been reorganized several times in the last decade. Two of its key diet-related outreach and education programs–the National Cholesterol Education Program and the National High Blood Pressure Education Program, which would have been the leading outreach proponent for NSRI–have receded from view, with perfunctory descriptions on the agency web site, no functioning links to current activities if there are any or to updated program pages, and no clear leadership or place in the agency’s organizational chart. But the need for them certainly hasn’t ended.

Voluntary compliance programs don’t have a great track record in the processed food industry. Look at the recent Smart Choices nutrition labeling program fiasco (see under, Froot Loops) from October.

Starting a national  program like this with voluntary compliance as a key component means the designers don’t think there’s much way to enforce the changes other than persuasion. It also means the government doesn’t have the tools, the money, or–and here is the crux of it–the will to enforce even modest limits on sodium content. Both the AHA and the AMA have been working on the FDA for years to get salt off the “generally harmless Continue reading

Misunderstanding Salt Research: Bon Appetit’s Shameful “Health Wise” Column

I started this blog last spring more or less just to test out blogging lightheartedly about food. However, I have just read Bon Appetit‘s appalling “Health Wise” column from the May issue, “The Saline Solution” by John Hastings.

I do actually love to cook and eat well, and that’s my main purpose for this blog, but seeing this kind of blithely irresponsible “health” advice on salt makes my blood boil (not appetizing). Worse, it starts dragging me back to my work roots and up on my soapbox (also not appetizing, though kind of fun), because I trained as a biochemist and worked for several years as a science journalist. I worked for the National Heart, Lung, and Blood Institute at NIH at the time some of the bigger studies Hastings refers to were first being published. It was my job to know about them and write about them in plain (and preferably short) English for Congress and the public. To do it I talked to national experts, interviewed the leaders of the National High Blood Pressure Education Program, and combed through a century’s worth of research on salt and high blood pressure.

But you don’t have to be a scientist to find this stuff out. Descriptions of the studies AND their updates AND the reasoning behind the basic public health guidelines calling for Americans to watch their salt AND how to do it without eating a restricted diet of cardboard and baby cereal are all easily available from the NHLBI web site or the American Heart Association.

Hastings, a former editor of Prevention and health column contributor to O, the Oprah Magazine, is someone you’d expect to be reasonably accurate in reporting health research findings. But here he gets the science on salt and high blood pressure just about as backwards and upside down as he possibly can.

Worse yet, he does it in a strangely breezy, cheerleading tone that’s really hard to believe.

Hastings’ argument goes something like this:

…here’s a little secret: salt isn’t a problem. If that sounds crazy, it’s because the public health message about salt causing high blood pressure has been very, very effective, and it’s backed by reams of scientific research…Upon this, nearly everyone agrees. The controversy arises when you ask experts about the connection between salt intake and high blood pressure…All of this is fantastic news for those of us who are already cooking with high-quality meats and farmers’-market produce…

Did you follow all that? Probably you felt like you did for the few seconds you were reading it, but look again and you start to pick out the self-contradictions–“If it sounds crazy” that salt isn’t a problem, “it’s because the public health message that salt causes high blood pressure… is backed by reams of scientific research.”

Well, yes it is. The way Hastings phrases it, you’re supposed to think that was a bad thing, that health research in general and carefully designed tests of the effects of diet on cardiovascular health in particular are part of some kind of unnamed conspiracy against the public’s right to eat every bit of salt it can get.  Personally, I’d rather that broad public health messages were backed by reams of scientific research rather than by some diet guru or brand-name chef’s nutritional fantasy that will help sell his next book or tv program, or–more realistically–by corporate marketing and pressure campaigns from big pharma and big agro. Of course, it’s less profitable if people simply eat less salt–and less processed food–and never develop hypertension in the first place than if they eat salt like it’s going out of style and call it gourmet, and then have to make up for their diet by taking hypertension pills…hmm. Food, Inc., anyone?

“Upon this nearly everyone agrees”, but somehow there’s still a great controversy over it? Really? No. Not really.

The vast majority of salt researchers look at the bulk of the study results and conclude–repeatedly, for decades now–that salt is, in fact, a direct and modifiable risk factor for hypertension (high blood pressure). Which is both a disease in its own right and a leading risk factor for heart disease, stroke, and chronic kidney disease. Combine that with the fact that the average current salt intake is about twice what the consensus guidelines recommend and that more than half the adult population in the U.S. is crossing the line into overweight and obesity–and…well, yes.

Salt IS actually a health problem for most people. Gee.

The Bon Appetit article is a jumble of self-contradictions and serious misinterpretations of the findings from two older salt research studies, one of which has since been revised,  plus a cherry-picking recent review that comes to a different conclusion about salt than most of the other reviews of the same data on diet and health. That one comes from the lab of Mickey Alderman, an otherwise eminent researcher who just happens to be a long-time, much-trumpeted advisor and consultant for the Salt Institute.

Hastings  doesn’t indicate that he interviewed the man or even recognized his name on the journal article, but he should have. Anytime somebody in the media wants to come up with the magical–and really, really popular–conclusion that lots of salt, any day, any time, anywhere, please add more, is perfectly harmless and even good for you, they go to Mickey Alderman because they can paint him as a lone hero against the Food Police (the typical name they give the National Institutes of Health and the American Heart Association in such cases). Because what Alderman will say–with precision, but with disregard for the bigger public health picture–is that high salt intake isn’t directly proven to cause death from cardiovascular disease.

And it isn’t. It can’t be proven directly in a well-controlled diet study large enough to reach statistical significance, because that would require thousands of participants to follow a carefully prepared diet throughout their entire lifetimes, with no deviations for dates, wedding receptions, pizza parties, etc., and it would take 50-75 years to collect the majority of the data. You’d literally have to wait until most of the participants died before you could make a public health recommendation about salt. And the cost of doing that study “right” would run into the billions. It would bankrupt the federal science budget. And maybe a few other budgets as well.

That’s why the NHLBI and the AHA have sponsored studies that look at signs of developing cardiovascular illness–heart attacks, stroke, phlebitis, high blood pressure, kidney disease–rather than death. When you look at these ailments, you find that dietary salt actually matters quite a bit–contrary to what Hastings thought he understood from the studies he mentions.

Continue reading